Artificial intelligence helping diagnosis of rare diseases with oral expressions
This Data Challenge is led by Pr Agnès Bloch-Zupan (PU-PH professor, clinician, rare disease expert, coordinator of the Strasbourg University Hospital, Reference center for rare oral and dental diseases and associated network, researcher at IGBMC, Université de Strasbourg, CNRS- UMR7104, INSERM U1258) and supported by the D-IA-GNO-DENT consortium. This consortium (members below), in partnership with the Health Data Hub, proposes a Data Challenge on the theme of rare dental diseases.
Introduction of the DIAGNODENT data challenge by Pr Agnès Bloch-Zupan (video from Health Data Hub)
Moving from wandering to diagnosis
Join the D-IA-GNO-DENT Challenge and develope an AI solution to aid in the diagnosis of rare dental diseases based on the analysis of photographs and X-rays of the mouth and teeth. These genetic diseases, which affect multiple organs and systems, are recognised through abnormalities in teeth fixed over time by mineralisation.
The goal : to promote access to early detection of rare oral diseases for patients and health professionals
The expected benefit : to reduce the diagnostic wandering of affected individuals.
Oral pathologies or anomalies are often the little known expression of rare diseases of genetic origin. These anomalies are receiving increasing attention because of their diagnostic or even predictive character. They are classified into dental anomalies of number, shape, size, structure, root formation and eruption and correspond to specific developmental and genetic problems. They are fixed in time by mineralisation. They are isolated or associated with other symptoms in syndromes.
900 rare diseases have a dento/oro/facial component. Clinical diagnoses and identification of the genes involved are difficult to make and to implement, leading patients and their families into diagnostic wandering. However, there are diagnostic signatures recognised by experts in the field and supported by phenotype/genotype correlations (D4/phenodent database/NGS GenoDENT panel).
FOR WHOM ?
BY WHOM ?
Designed for rare disease patients
Used by doctors and medical research
Input and output data
Decrease diagnostic wandering Accelarate care in the « right » care pathway
Access to enhanced knowledge of rare diseases Acces to rapid expertise
Inputs : images, reports, diagnostic signatures... Output : a (pre-)diagnosis of suspected rare disease with oral manifestations
A BIG CHALLENGE !
We have to make a limited set of data speak for itself; we are in the field of rare tooth enamel diseases, but also of precision medicine.
Data / Cohorts
Amelogenesis imperfecta --> 200 + 20
Dentine anomalies --> 50
Control --> 100
Intraoral colour photographs (4 to 10/individuals)
Challenge & Rewards
Timeline : The D-IA-GNO-DENT Challenge will take place in April 2023 and will be hosted on our platform, Trustii.io.
To participate in the D-IA-GNO-DENT, sign-up at https://app.trustii.io (as data scientist) and complete this form to gain access to the data challenge once it's available.
3 prizes will be awarded to the teams that provide the most effective* algorithms, including a first prize of €20 000
To participate in the DIAGNODENT Challenge, apply by completing this form and sign-up at https://app.trustii.io (as data scientist).
Fully managed development Environment
DIAGNODENT challenge will be hosted at Trustii.io data challenge platform, Data scientists participating in the DIAGNODENT Challenge will have access to a hosted Jupyter notebook with free GPU resources to develop their models.